Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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2,356
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2,370
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2,356
R&D Systems™ BGC 20-1531 hydrochloride
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. High affinity and selective EP4 antagonist
2,357
R&D Systems™ Aliskiren hemifumarate
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent renin inhibitor; antihypertensive
| Product Type | Aliskiren hemifumarate |
|---|---|
| Molecular Weight (g/mol) | 609.83 |
| Purity | >99% |
2,358
R&D Systems™ BIX 02189
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective MEK5 and ERK5 inhibitor
| Inhibitors | BIX 02189 |
|---|---|
| Product Type | BIX 02189 |
| Molecular Weight (g/mol) | 440.54 |
| Purity | >98% |
2,359
R&D Systems™ ZAP 180013
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Zap70 inhibitor; inhibits interaction with ITAMs
| CAS | 873080-25-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 5-Chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-4-pyrimidinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H17Cl2N3O4S |
2,360
R&D Systems™ Dynapyrazole A
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Hedgehog signaling inhibitor; dynein inhibitor
| Target | Hedgehog Signaling Inhibitors |
|---|---|
| CAS | 2226517-75-3 |
| Purity | 98% |
| Chemical Name or Material | 2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H12ClIN4O |
2,361
R&D Systems™ Saracatinib
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective Src tyrosine kinase family inhibitor; anticancer; antiviral; orally bioavailable
2,362
R&D Systems™ OUL 35
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective PARP-10 inhibitor
| CAS | 6336-34-1 |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at 4°C |
| Synonym | 4,4′-Oxybis[benzamide] |
| Molecular Formula | C14H12N2O3 |
| Formula Weight | 256.26 |
2,363
R&D Systems™ StemRegenin 1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Aryl hydrocarbon receptor (AhR) antagonist; promotes HSC expansion and engraftment
2,364
R&D Systems™ INCB 3284 dimesylate
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 887401-93-6 Molecular Formula: C28H39F3N4O10S2
| CAS | 887401-93-6 |
|---|---|
| Molecular Formula | C28H39F3N4O10S2 |
2,365
R&D Systems™ TY 52156
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. S1P3 receptor antagonist
| Product Type | TY 52156 |
|---|---|
| Molecular Weight (g/mol) | 364.27 |
| Purity | >98% |
2,366
R&D Systems™ PDD 00017272
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent PARG inhibitor
| Target | PARG Inhibitors |
|---|---|
| CAS | 1945950-20-8 |
| Purity | 98% |
| Chemical Name or Material | 1-[(2,4-Dimethyl-5-thiazolyl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-dioxo-6-quinazolinesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H25N5O4S3 |
2,367
R&D Systems™ TH 10785
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. OGG1 activator
| Target | Glycosylase Activators |
|---|---|
| CAS | 1002801-51-5 |
| Purity | 0.98 |
| Chemical Name or Material | N-Cyclohexyl-2-cyclopropyl-4-quinazolinamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H21N3 |
2,368
R&D Systems™ KN-62
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 127191-97-3 Molecular Formula: C38H35N5O6S2
| CAS | 127191-97-3 |
|---|---|
| Molecular Formula | C38H35N5O6S2 |
2,369
R&D Systems™ CGP 57380
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 522629-08-9 Molecular Formula: C11H9FN6
| CAS | 522629-08-9 |
|---|---|
| Molecular Formula | C11H9FN6 |
2,370
R&D Systems™ PF 3084014 hydrobromide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent γ-secretase inhibitor
| Target | gamma-Secretase |
|---|---|
| CAS | 1962925-29-6 |
| Purity | 98% |
| Chemical Name or Material | (2 S)-2-[[(2 S)-6,8-Difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]amino]-N-[1-[2-[(2,2-dimethylpropyl)amino]-1,1-dimethylethyl]-1 H-imidazol-4-yl]pentanamide dihydrobromide |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C27H41F2N5O.HBr |
| Formula Weight | 651.47 |